The study examined childhood trauma, perceived social support, and postpartum depression in married women with first-time miscarriages. After reviewing the literature, these hypotheses were formed. 1).Childhood trauma, perceived social support, and postpartum depression are significantly associated with newly married women with first miscarriage. 2)Early trauma and support networks are two major contributors to the new-onset maternal depression in newly married women experiencing a first perinatal loss. 3). There are significant family system differences in early trauma, support networks, and new-onset maternal depression for newly married women experiencing a first perinatal loss. The research has surveyed 250 newly married females in the b/t age group of 18–35 years after their first loss event. The sample includes public and private hospitals in Lahore and Faisalabad. Calculations were done according to the psychological measures: 1)Childhood Trauma Questionnaire 2)Perceived Social Support, and 3) Edinburgh Postnatal Depression Scale. Data analysis was done through SPSS.